Deleted genes were shown in the simplified metabolite pathways. Circles and lines represent metabolites and reactions, respectively. Genes related to the trehalose metabolism, glyoxylate pathway, and the global regulation were shown in round rectangles. Abbreviations: Glc: glucose, G6P: glucose 6-phosphate, F6P: fructose 6-phosphate, FBP: fructose 1,6-bisphosphate,DHAP: dihydroxyacetone phosphate, GAP: glyceraldehyde 3-phosphate, 13BPD: 1,3-bisphosphoglycerate, 3PG: 3-phosphoglycerate, 2PG: 2-phosphoglycerate, PEP: phosphoenolpyruvate, Pyr: pyruvate, AcCoA: acetyl-coenzyme A, 6PGL: 6-phosphogluconolactone, 6PG: 6-phosphogluconate, Ru5P: ribulose 5-phosphate, R5P: ribose 5-phosphate, Xu5P: xylulose 5-phosphate, S7P: sedoheptulose 7-phosphate, E4P: erythrose 4-phosphate, ACALD: acetoaldehyde, ETOH: ethanol, CIT: citrate, ISOCIT: isocitrate, ACO: anonitate, AKG: alpha-ketoglutarate, SucCOA: succinyl coenzyme A, SUC: succinate, FUM: fumarate, MAL: malate, OXA: oxaloacetate, G3P: glycerol-3-phosphate, GLYC: glycerol.