Fig 6. Some functional couplings observed in different microorganisms are predicted by the model.

Predicted couplings between the ATP and NADH production rates (A), between the sum of fluxes per glucose uptake rate and the ATP yield (B), and between the growth rate per sum of fluxes and the sum of fluxes per glucose uptake rate (C). Shades of white to blue denote null to high frequency, respectively. The red line in panel A corresponds to the linear correlation proposed by [73] from energy production fluxes estimated using ¹³C-flux data.