TABLE 1.
Carbapenemase | No. with indicated temocillin disk test result |
No. with indicated faropenem disk test result |
No. with indicated OXA-48 disk test result |
No. with indicated HI OXA-48 disk test result |
No. with indicated ICT result |
MIC range (mg/liter) |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P | N | P | N | P | N | P | N | P | N | ETP | IPM | MEM | DOR | |
Ambler class D (n = 84) | ||||||||||||||
OXA-48 (n = 59) | 59 | 45 | 14 | 35 | 24 | 59 | 59 | 0.5 to >32 | 0.5 to >32 | 0.25 to >32 | 0.25 to >32 | |||
OXA-162 (n = 7) | 7 | 7 | 5 | 2 | 7 | 7 | 2 to >32 | 1 to 8 | 0.5 to >32 | 0.25 to >32 | ||||
OXA-181 (n = 8) | 8 | 2 | 6 | 3 | 5 | 8 | 8 | 1 to >32 | 0.25 to >32 | 0.25 to >32 | 0.25 to >32 | |||
OXA-204 (n = 1) | 1 | 1 | 1 | 1 | 1 | >32 | 8 | >32 | >32 | |||||
OXA-232 (n = 7) | 7 | 7 | 1 | 6 | 7 | 7 | 2 to >32 | 0.5 to 32 | 0.25 to >32 | 0.25 to >32 | ||||
OXA-244 (n = 2) | 2 | 2 | 2 | 1 | 1 | 2 | 2 to >32 | 0.5 to 32 | 0.25 to >32 | 0.12 to >32 | ||||
Total (%) | 84 (100) | 0 (0) | 48 (57.1) | 36 (42.9) | 45 (53.6) | 39 (46.4) | 83 (98.8) | 1 (1.2) | 84 (100) | 0 (0) | ||||
Ambler class A (n = 14) | ||||||||||||||
KPC-2 (n = 13) | 8 | 5 | 0 | 13 | 0 | 13 | 2 | 11 | 0 | 13 | 16 to >32 | >32 | >32 | 8 to >32 |
KPC-3 (n = 1) | 1 | 1 | 1 | 1 | 1 | >32 | >32 | >32 | >32 | |||||
Total (%) | 9 (64.3) | 5 (35.7) | 0 (0) | 14 (100) | 0 (0) | 14 (100) | 2 (14.3) | 12 (85.7) | 0 (0) | 14 (100) | 16 to >32 | >32 | >32 | 8 to >32 |
Ambler class B (n = 27) | ||||||||||||||
GIM-1 (n = 2) | 2 | 2 | 2 | 2 | 2 | >32 | >32 | >32 | >32 | |||||
NDM-1 (n = 4) | 4 | 4 | 4 | 4 | 4 | >32 | 8 to >32 | >32 | >32 | |||||
NDM-7 (n = 1) | 1 | 1 | 1 | 1 | 1 | >32 | >32 | >32 | >32 | |||||
VIM-1 (n = 16) | 15 | 1 | 0 | 16 | 0 | 16 | 0 | 16 | 0 | 16 | 0.5 to >32 | 1 to >32 | 0.25 to >32 | 0.12 to >32 |
VIM-26 (n = 2) | 2 | 2 | 2 | 2 | 2 | >32 | >32 | >32 | >32 | |||||
VIM-27 (n = 1) | 1 | 1 | 1 | 1 | 1 | >32 | >32 | >32 | >32 | |||||
VIM-29 (n = 1) | 1 | 1 | 1 | 1 | 1 | >32 | >32 | >32 | >32 | |||||
Total (%) | 26 (96.3) | 1 (3.7) | 0 (0) | 27 (100) | 0 (0) | 27 (100) | 0 (0) | 27 (100) | 0 (0) | 27 (100) | 0.25 to >32 | 1 to >32 | 0.25 to >32 | 0.12 to >32 |
No carbapenemases (n = 41) | ||||||||||||||
Total (%) | 11 (26.8) | 30 (73.2) | 1 (2.4) | 40 (97.6) | 0 (0) | 41 (100) | 0 (0) | 41 (100) | 0 (0) | 41 (100) | 0.12 to >32 | 0.25 to >32 | 0.016 to >32 | 0.016 to >32 |
HI OXA-48 disk test, high-inoculum OXA-48 disk test; P, positive; N, negative; ETP, ertapenem; IPM, imipenem; MEM, meropenem; DOR, doripenem.