TABLE 2.
Clinical characteristics of patients with M. avium complex pulmonary diseasea
| Parameter | Mean ± SD |
Pb | |||
|---|---|---|---|---|---|
| Total (n = 34) | Culture conversion (n = 19) | Recurrence (n = 7) | Nonconversion (n = 8) | ||
| Age (yrs) | 66.8 ± 9.1 | 67.9 ± 8.4 | 61.4 ± 8.9 | 68.6 ± 9.9 | 0.2426* |
| Female (no. of patients) | 30 | 18 | 6 | 6 | 0.3385† |
| Body mass index (kg m−2) | 18.3 ± 2.6 | 18.3 ± 2.0 | 19.6 ± 3.0 | 17.2 ± 3.4 | 0.3498* |
| No. of patients | |||||
| Former smokers | 7 | 1 | 3 | 3 | 0.0439‡ |
| Daily alcohol intake | 2 | 0 | 2 | 0 | 0.0533‡ |
| Underlying lung disease | 5 | 3 | 0 | 2 | 0.5181‡ |
| Comorbidity (no. of patients) | |||||
| Diabetes mellitus | 3 | 3 | 0 | 0 | |
| Cardiovascular disease | 3 | 1 | 1 | 1 | |
| Hyperlipidemia | 3 | 1 | 0 | 2 | |
| Other | 4 | 2 | 1 | 1 | |
| Disease type (no. of patients) | |||||
| NB disease | 32 | 18 | 7 | 7 | 0.5187‡ |
| FC disease | 2 | 1 | 0 | 1 | |
| Extent of diseasec | 7.5 ± 3.6 | 7.4 ± 0.8 | 7.0 ± 1.4 | 8.5 ± 1.3 | 0.6956* |
| MAC species (no. of strains) | |||||
| M. avium | 20 | 11 | 7 | 2 | |
| M. intracellulare | 12 | 8 | 0 | 4 | 0.0378‡ |
| Both Mycobacterium species | 2 | 0 | 0 | 2 | |
| Albumin level (g/dl) | 3.7 ± 0.4 | 3.8 ± 0.4 | 3.6 ± 0.4 | 3.5 ± 0.4 | 0.3672* |
| Total cholesterol level (mg/dl) | 193.6 ± 35.1 | 199.9 ± 40.5 | 189.1 ± 25.1 | 182.5 ± 28.6 | 0.4199* |
| Erythrocyte sedimentation rate (mm/h) | 38.5 ± 30.7 | 30.5 ± 7.0 | 19.7 ± 7.5 | 45.1 ± 40.3 | 0.9103* |
| C-reactive protein level (mg/dl) | 0.6 ± 1.2 | 0.6 ± 1.2 | 0.2 ± 0.4 | 1.2 ± 1.3 | 0.2376* |
a
Data are presented as means ± the SD, except as noted otherwise in column 1. FC disease, fibrocavitary disease; NB disease, nodular bronchiectatic disease.
b
P values were calculated using either the Kruskal-Wallis test (*) for continuous values or the chi-square test (†) or Fisher exact test (‡) for categorical variables.
c
The number of CT segments in which MAC lesions were present.