FIG 1.
ROC curves for determination of anti-Coccidioides IgG and IgM antibody cutoff values. (A) The ROC curve recommended an OD450/620 cutoff value of 0.133 for IgG detection. The sensitivity with this cutoff value was 87.4% (n = 103) and the specificity was 92.3% (n = 220), with an AUC of 0.957 (95% CI, 0.928 to 0.977) and a standard error of 0.0109 (P < 0.0001). (B) The ROC curve recommended an OD450/620 cutoff value of 0.137 for IgM detection. The sensitivity with this cutoff value was 61.2% and the specificity was 96.4%, with an AUC of 0.887 (95% CI, 0.846 to 0.921) and a standard error of 0.0227 (P < 0.0001).