TABLE 1.
Comparison of antibody detection using different antibody assaysa
| Test | Sensitivity (%) using cases | Specificity (%) using controlsb |
|---|---|---|
| MVista IgG | 87.4 | 90.0 |
| MVista IgM | 61.2 | 95.3 |
| MVista IgG or IgM | 88.3 | 90.0 |
| IDCF | 53.4 | 98.8 |
| IDTP | 33.0 | 100 |
| IDCF or IDTP | 60.2c | 98.8c |
| CF | 64.5c | NA |
a
The numbers of cases and controls were as follows: MVista EIA, 103 and 170; ID, 103 and 164; CF, 62 and 0. IDCF, immunodiffusion with the CF antigen; IDTP, immunodiffusion with the TP antigen; CF, complement fixation; NA, not available.
b
Controls from areas in which the disease is endemic included controls from Bakersfield, California, and Tucson, Arizona, and clinical controls from Tucson, Arizona.
c
P < 0.001, in comparison with the MVista assay.