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. 2017 Feb 23;85(3):e01041-16. doi: 10.1128/IAI.01041-16

FIG 3.

FIG 3

Ceruloplasmin (CP) is a molecular source of urinary Cu during UTI. (A) Representative immunoblot assay with UTI (U; n = 2) and healthy (H; n = 2) human urine samples probed with anti-CP antibody. +ve, human CP (20 ng). (B) Urinary CP levels were measured by ELISA. ***, P < 0.001; Kruskal-Wallis test with Dunn's posttest. UPEC, n = 30; K. pneumoniae (KP), n = 10; P. mirabilis (PM), n = 17; healthy controls, n = 40. (C) Urinary Cu and ceruloplasmin levels are positively correlated in UTI samples. Pearson's correlation coefficient was determined for urinary Cu and ceruloplasmin levels (r = 0.58 and P < 0.0001). UTI urine samples (UPEC, KP, and PM), n = 57.