TABLE 1.

MICs of various β-lactams for A. baumannii strains IOMTU442 and IOMTU448 and E. coli DH5α transformed with PER-7- or PER-8-encoding plasmids

Antibiotic(s)a	MIC (mg/liter)
	IOMTU442	IOMTU448	pHSG398/PER-7	pHSG398/PER-8	pHSG398
Amikacin	>1,024	8	NDb	ND	ND
Ampicillin	>1,024	>1,024	32	16	2
Ampicillin-sulbactam	64	64	2	2	2
Arbekacin	>1,024	2	ND	ND	ND
Aztreonam	>1,024	>1,024	8	4	≤0.063
Cefepime	512	512	0.125	0.25	≤0.063
Cefmetazole	256	>1,024	1	1	1
Cefotaxime	512	>1,024	16	8	≤0.063
Cefoxitin	512	>1,024	4	4	4
Cefpirome	256	256	≤0.063	≤0.063	≤0.063
Ceftazidime	>1,024	512	32	64	0.5
Cephradine	>1,024	>1,024	128	128	16
Ciprofloxacin	32	32	ND	ND	ND
Colistin	0.25	0.5	ND	ND	ND
Fosfomycin	128	256	ND	ND	ND
Gentamicin	>1,024	>1,024	ND	ND	ND
Imipenem	2	8	0.125	0.125	≤0.063
Kanamycin	>1,024	>1,024	ND	ND	ND
Levofloxacin	32	8	ND	ND	ND
Meropenem	1	16	≤0.063	≤0.063	≤0.063
Moxalactam	128	128	≤0.063	≤0.063	≤0.063
Penicillin G	>1,024	>1,024	64	64	32
Piperacillin	>1,024	512	4	4	2
Piperacillin-tazobactam	64	256	2	2	2
Tigecycline	0.25	0.5	ND	ND	ND

^aThe ratio of ampicillin to sulbactam was 2:1. The ratio of piperacillin to tazobactam was 4:1.

^bND, not determined.