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Sigmoid inhibitory fit for PAO1 between the log10 CFU/lung at 24 h and the PK/PD indices for ELF, namely, AUCELF/MIC (A), Cmax, ELF/MIC (B), and T>MIC, ELF (C), and for plasma, namely, fAUCPlasma/MIC (D), fCmax, Plasma/MIC (E), and fT>MIC, Plasma (F). R2 is the coefficient of determination. The broken line represents the mean bacterial burden in lungs at the start of treatment.
