TABLE 1.

Selected input parameters^a

Variable description	Baseline value	Reference(s)
Protection from reinfection in latent infection state	0.5	41, 42
Proportion progressing rapidly to active TB	0.15	43
Baseline life expectancy (yr)	70	44
TB-specific mortality rate/yr	0.17	45
Probability of endogenous reactivation over the patient's lifetime	5%	46
Rate of diagnosis and treatment initiation/yr	0.69	21
Relative infectiousness of patients on ineffective treatment	0.2	47
Rate of spontaneous recovery from active TB/yr	0.17	45
% discontinuing treatment prior to completion
First-line treatment	6	21
Second-line treatment	23	35
% experiencing early relapse
Drug-sensitive TB	4	48, 49
RIF-resistant TB	16	50
FQ-resistant TB	12	50
PZA-resistant TB	8	14

^aAdditional details are provided in Table S3 in the supplemental material.