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. 2017 Feb 23;61(3):e00498-16. doi: 10.1128/AAC.00498-16

TABLE 2.

Outcomes upon treatment completion, by resistance profile and treatment regimena

Final drug resistance profile Probability (%) of:
Cure
Early relapse after cure
First-line agents Second-line agents First-line agents Second-line agents
Drug susceptible 89–99 4
RIFr 40–64 89–94 16 4
FQr 89–99 4
PZAr 83–90 8
RIFr, FQr 40–64 57–74 16 12
RIFr, PZAr 32–59 76–86 16 8
FQr, PZAr 83–90 8
RIFr, FQr, PZAr 32–59 47–68 16 12
a

Additional details are provided in Table S1 in the supplemental material. —, not applicable, as the second-line regimen is assumed to be given only to patients with resistance to at least rifampin; RIFr, rifampin resistance; PZAr, pyrazinamide resistance; FQr, fluoroquinolone resistance.