Table 2.

Transitional hazard ratios for multi-state prediction model:

Predictor	T1: Prevalent HF to HF hospitalization		T2: Prevalent HF to Death		T3: HF hospitalization to Death
	HR	95% CI	HR	95% CI	HR	95% CI
Age per 10 year increase	1.09	1.02-1.16	1.22	1.13-1.32	1.09	1.00-1.19
Female gender	0.81	0.69-0.96	0.69	0.57-0.83	0.93	0.75-1.17
NYHA III vs II	1.62	1.41-1.85	1.41	1.21-1.64	1.38	1.16-1.65
LVEF per 10% increase	0.73	0.66-0.80	0.76	0.68-0.85	0.88	0.77-1.01
Creatinine per 1mg/dl increase	2.22	1.83-2.68	1.62	1.30-2.01	1.78	1.39-2.29
Sodium (per 10mEQ/L increase)	0.77	0.68-0.88	0.77	0.68-0.88	0.77	0.68-0.88
Systolic Blood Pressure per 10mmHg increase	0.91	0.87-0.94	0.98	0.94-1.02	0.94	0.89-0.99
Weight per 10kg increase	0.92	0.88-0.96	0.86	0.82-0.91	0.84	0.79-0.90
Diabetes mellitus	1.50	1.30-1.72	1.47	1.26-1.71	1.13	0.94-1.36
Ischemic etiology	0.90	0.78-1.03	1.15	0.97-1.35	1.13	0.93-1.37
Atrial fibrillation	1.21	1.05-1.40	1.28	1.09-1.50	0.89	0.73-1.08
Prior stroke	1.28	1.03-1.60	1.52	1.22-1.89	1.16	0.87-1.53

HR indicates hazard ratio, CI confidence interval, HF heart failure, NYHA New York Heart Association, LVEF left ventricular ejection fraction