Table 3.
Patient A (Q1) | Patient B (Q2) | Patient C (Q3) | Patient D (Q4) | Patient E (Q5) | ||
---|---|---|---|---|---|---|
Age (yrs) | 66 | 64 | 69 | 65 | 75 | |
Gender (M/F) | M | M | F | M | M | |
NYHA Class (II or III) | II | II | III | II | III | |
LVEF (%) | 38 | 35 | 30 | 29 | 31 | |
Creatinine (mg/dl) | 1.6 | 2.0 | 0.7 | 1.2 | 1.1 | |
Serum sodium (mEq/L) | 141 | 135 | 141 | 140 | 135 | |
Systolic blood pressure (mmHg) | 152 | 160 | 122 | 140 | 115 | |
Weight (kg) | 110 | 115 | 84.3 | 78 | 105 | |
Diabetes (Y/N) | − | − | + | + | + | |
Ischemic etiology (Y/N) | − | + | + | + | + | |
Atrial fibrillation (Y/N) | − | − | − | − | + | |
Prior stroke (Y/N) | − | − | − | − | − | |
1 yr probabilities of being in a given outcome state | Alive without HFH | 94.3% | 91.9% | 89.0% | 87.1% | 77.1% |
HFH, still alive | 3.6% | 4.6% | 6.1% | 6.3% | 12.5% | |
Death without HFH | 1.9% | 3.0% | 4.1% | 5.7% | 8.5% | |
HFH followed by death | 0.2% | 0.5% | 0.8% | 0.9% | 1.9% | |
3 yr probabilities of being in a given outcome state | Alive without HFH | 84.9% | 78.8% | 72.0% | 67.3% | 48.0% |
HFH, still alive | 7.8% | 9.3% | 11.1% | 11.1% | 19.4% | |
Death without HFH | 5.7% | 8.9% | 11.7% | 15.9% | 11.0% | |
HFH followed by death | 1.6% | 3.0% | 5.2% | 5.7% | 21.6% | |
6 yr probabilities of being in a given outcome state | Alive without HFH | 72.5% | 62.5% | 52.3% | 45.4% | 23.4% |
HFH, still alive | 10.7% | 11.1% | 11.5% | 10.6% | 15.5% | |
Death without HFH | 11.4% | 16.8% | 21.3% | 28.1% | 33.7% | |
HFH followed by death | 5.4% | 9.6% | 14.9% | 15.9% | 27.4% |
Q1 refers to quintile 1 (lowest risk), Q2 quintile 2, Q3 quintile 3, Q4 quintile 4, Q5 quintile 5 (highest risk), M male, F female, NYHA New York Heart Association, LVEF left ventricular ejection fraction, HFH heart failure hospitalization, (+) refers to present and (−) refers to absent at baseline