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. Author manuscript; available in PMC: 2017 Aug 11.
Published in final edited form as: Chem. 2016 Aug 11;1(2):320–327. doi: 10.1016/j.chempr.2016.07.007

Figure 2.

Figure 2

(a) TNFα secretion of J774.2 cells in the presence of the NPs, with and without LPS stimulation after 3h incubation. Values normalized against the positive control (Cell + LPS). (b) Cellular uptake of the different NPs for both LPS challenged and unchallenged conditions. (c) ROS generation of J774.2 cells under the same experimental conditions (LPS challenge, 24 h). Values normalized against the normal cell response. (d) Cell viability of J774.2 after 24 h incubation with the different NPs and LPS measured by trypan blue. (e) MTS assay indicating the metabolism (vitality) of cells after 24 h exposure with NPs and LPS. Values normalized against the responses of untreated cells. (*) indicates statistically significant difference and (n.s.s.) indicates lack of statistically significant difference relative to control (Cells alone in gray or Cell+LPS in red).