Table 1.
Association between linc-UBC1 expression and clinic o-pathological features in 96 patients with colorectal cancer
| Factors | All cases, n (%) | linc-UBC1 expression
|
χ2 | P-value | |
|---|---|---|---|---|---|
| Low, n (%) | High, n (%) | ||||
| Age at diagnosis (years) | |||||
| <60 | 49 (51.0) | 25 (51.0) | 24 (49.0) | 0.042 | 0.838 |
| ≥60 | 47 (49.0) | 23 (48.9) | 24 (51.1) | ||
| Gender | |||||
| Male | 62 (64.6) | 29 (46.8) | 33 (53.2) | 0.729 | 0.393 |
| Female | 34 (35.4) | 19 (55.9) | 15 (44.1) | ||
| Tumor location | |||||
| Colon | 49 (51.0) | 23 (46.9) | 26 (53.1) | 0.375 | 0.540 |
| Rectum | 47 (49.0) | 25 (53.2) | 22 (46.8) | ||
| Tumor size | |||||
| <5.0 cm | 50 (52.1) | 34 (68.0) | 16 (32.0) | 13.523 | 0.001 |
| ≥5.0 cm | 46 (47.9) | 14 (30.4) | 32 (69.6) | ||
| Differentiation status | |||||
| Poor | 35 (36.5) | 14 (40.0) | 21 (60.0) | 2.203 | 0.138 |
| Moderate or high | 61 (63.5) | 34 (55.7) | 27 (44.3) | ||
| Depth of invasion | |||||
| T1 + T2 | 18 (18.8) | 13 (72.2) | 5 (27.8) | 4.376 | 0.036 |
| T3 + T4 | 78 (81.2) | 35 (44.9) | 43 (55.1) | ||
| Lymph node metastasis | |||||
| N0 | 58 (60.4) | 35 (60.3) | 23 (39.7) | 6.672 | 0.012 |
| N1 + N2 | 38 (39.6) | 13 (34.2) | 25 (65.8) | ||
| Distant metastasis | |||||
| M0 | 85 (88.5) | 43 (50.6) | 42 (49.4) | 0.103 | 0.749 |
| M1 | 11 (11.5) | 5 (45.5) | 6 (54.5) | ||
| TNM stage | |||||
| I + II | 55 (57.3) | 33 (60.0) | 22 (40.0) | 5.151 | 0.023 |
| III + IV | 41 (42.7) | 15 (36.6) | 26 (63.4) | ||
Abbreviation: linc-UBC1, long non-coding RNA upregulated in bladder cancer 1.