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. 2017 Feb 22;10:1091–1100. doi: 10.2147/OTT.S125724

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© 2017 Wang et al. This work is published and licensed by Dove Medical Press Limited

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Down-regulation of miR-622 could inhibit migration and invasion of CRC cells. (A, B) miR-622 mRNA was remarkably decreased by transfection of miR-622 inhibitor compared to inhibitor control in SW1116 and SW480 cells detected by real time PCR. (C, D) Down-regulation of miR-622 could inhibit the migration and invasion of SW1116 and SW480 cells. Data are presented as mean ± standard deviation. Two tailed Student’s t-test was used to analyze the significant differences, **P<0.01. Scale bars 20 μm.

Abbreviations: miR-622, microRNA-622; DYRK2, dual specificity tyrosine phosphorylation-regulated kinase 2; CRC, colorectal cancer; PCR, polymerase chain reaction.