Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 1;28(5):645–660. doi: 10.1091/mbc.E16-11-0806

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Gibeaux et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

“ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology.

PMC Copyright notice

FIGURE 6: — Influence of cytoplasmic flow on nuclear movements and role of cMT number in movement balance. (A) The frequency of forward movements as a function of increasing cytoplasmic flow (from 0 to 0.02 μm/s). Simulation values are plotted in gray (three cMTs per nucleus) and orange (six cMTs per nucleus) and experimental values in blue. (B) Plot of the frequency of backward movements as a function of increasing cytoplasmic flow (from 0 to 0.02 μm/s). Colors as in A. (C) The ratio of movement frequencies (forward/backward) as a function of increasing cytoplasmic flow (from 0 to 0.02 μm/s). Colors as in A. (D) Simulated nuclear positions along time without flow (speed of 0 μm/s). The x-coordinates of the center of individual nuclei (1–5) are plotted in different colors, and the dashed line indicates the applied flow speed. Top, example of a simulation with three cMTs. Bottom, example of a simulation with six cMTs. (E) Simulated nuclear positions along time with a flow speed of 0.02 μm/s. Same explanation as D. (F) The ratio of movement frequencies (forward/backward) as a function of increasing cytoplasmic flow (from 0 to 0.05 μm/s). Colors as in A.