Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 1;28(5):673–680. doi: 10.1091/mbc.E16-06-0370

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Montaño-Gutierrez et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

“ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology.

PMC Copyright notice

FIGURE 3: — Known and novel interdependences among complexes revealed by RF. Highest separation quality thresholds are depicted by dashed lines. (A) A 2D diagram to visualize intersections between RF results for different complexes. Proteins above both thresholds (pink quadrant) associate with both complexes, whereas those above only one remain independent. (B) Possible scenarios of interdependence between complexes inferred from 2D RF plots. A hierarchical effect (bottom left) occurs when the RF of one complex (squares) brings up the other complex (triangles) but not vice versa. A third-group link (bottom right) is equivalent to a double hierarchical effect on the pink circle complex. Many three-group relationships exist; in the case shown, the circle complex is the only link between the triangle and square complexes. (C, D) A 2D interdependence plot of the CCAN (C and D, squares) vs. the Nup107-160/RanGap complex (C, triangles) and the SMC 5/6 complex (D, triangles).