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. Author manuscript; available in PMC: 2017 Jun 1.

Published in final edited form as: J Clin Toxicol. 2016 May 30;6(3):1000300. doi: 10.4172/2161-0495.1000300

Change in blood pressure in animals treated with midazolam. Upon obtaining baseline BP, mice were administered TPPU (i.p., 3 mg/kg) 1 h before injection of midazolam at 1.8 and 10 mg/kg. Blood pressure was recorded at baseline, at 45 min after TPPU or PEG400 administration, at 5 min after midazolam and then at 1, 2, 3, 4 h. ‘‘ symbol indicates start of TPPU or vehicle (PEG400) treatment, ‘’ symbol indicates start of DZP or vehicle (40% propylene glycol, 10% alcohol) treatment. Data are mean ± SEM. n=6 /group.

Inline graphic — Change in blood pressure in animals treated with midazolam. Upon obtaining baseline BP, mice were administered TPPU (i.p., 3 mg/kg) 1 h before injection of midazolam at 1.8 and 10 mg/kg. Blood pressure was recorded at baseline, at 45 min after TPPU or PEG400 administration, at 5 min after midazolam and then at 1, 2, 3, 4 h. ‘‘ symbol indicates start of TPPU or vehicle (PEG400) treatment, ‘’ symbol indicates start of DZP or vehicle (40% propylene glycol, 10% alcohol) treatment. Data are mean ± SEM. n=6 /group.