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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: J Clin Toxicol. 2016 May 30;6(3):1000300. doi: 10.4172/2161-0495.1000300

Figure 5.

Figure 5

Plasma and tissue epoxide-to-diol ratios in animals treated with DZP (10 mg/kg) and TPPU (3 mg/kg) or PEG400. Mice were administered with TPPU (i.p., 3 mg/kg) 1 h before injection of DZP. Samples were quantified by LC/MS/MS for the levels of ARA and LA epoxides and diols. Sum of EETs and DHETs include 8, 9-, 11, 12- and 14, 15- regioisomers (Panel A). Sum of EpOME and DiHOME include 9, 10- and 11, 12- regioisomers (Panel B). Data are mean ± SEM. n=6 /group. Asterisk indicates a statistically significant difference between PEG vs TPPU at 1 h time point.