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Tissue and plasma levels of TPPU and DZP in mice
| [TPPU] (µM) | ||
| Time after TPPU administration | Brain | Plasma |
| 50 min (5 min after DZP) | 32.8 ± 3.4 | 11.8 ± 0.6 |
| 105 min (1 h after DZP) | 27.8 ± 2 | 10 ± 0.3 |
| Time after DZP administration | [DZP] (µM) | |
| Brain | Plasma | |
| 5 min- DZP 10 mpk | 15 ± 3 | 3 ± 0.8 |
| 5 min- DZP 10 mpk+TPPU | 15 ± 3 | 7 ± 2 |
| 1 h- DZP 10 mpk | 1 ± 0.1 | 0.4 ± 0.05 |
| 1h- DZP 10 mpk + TPPU | 1 ± 0.1 | 0.4 ± 0.03 |
