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. 2017 Feb 22;12:1485–1497. doi: 10.2147/IJN.S126210

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© 2017 Wan et al. This work is published and licensed by Dove Medical Press Limited

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Representative photography of mouse after 8 days treatment with different formulations (A) and skinfold thickness measurement (B).

Notes: Each bar represents the mean ± SD of nine determinations. Significant differences were calculated using the ANOVA test (*P<0.05). The concentration of FK506 in each formulation was 1 mg/mL.

Abbreviations: ANOVA, analysis of variance; CP, clobetasol propionate; FK506, tacrolimus; IMQ, imiquimod; NIC, nicotinamide; NPs, nanoparticles; SD, standard deviation.