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. Author manuscript; available in PMC: 2017 Feb 27.
Published in final edited form as: Bioorg Med Chem. 2008 Mar 6;16(9):5277–5284. doi: 10.1016/j.bmc.2008.03.013

Figure 4.

Figure 4

Concentration curves for compounds 2 and 5 showing in vitro inhibition of PKA activity (background counts subtracted). Error bars indicate standard deviation. The uncorrected calculated IC50 values in this assay (using 125 μM ATP) are 0.94 and 1.28 μM, respectively.