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. 2017 Feb 24;5(4):e13102. doi: 10.14814/phy2.13102

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© 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Cardiac parameters. Symbol legends for the four experimental days; exenatide (squares), GLP‐1 (triangles), GLP‐1_9–36amide (inverted triangles), Saline (circles). (A) Heart rate: Days were compared by a two‐way ANOVA (injection (P = 0.0162), time (P = 0.0038), and injection × time (P = 0.082)). Post hoc testing (Tukey) yielded a significant difference, GLP‐1 versus saline & GLP‐1_9–36amide (*). (B) Stroke volume: Days were compared by a two‐way ANOVA (injection (P = 0.51), time (P = 0.0050), injection × time (P > 0.99)). (C) Cardiac output: Days were compared by a two‐way ANOVA (injection (P = 0.92), time (P = 0.66), and injection × time (P > 0.99)). Data are means (SEM). Two‐sided P < 0.05 were considered significant.