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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: J Pediatr. 2016 Dec 1;182:21–27.e2. doi: 10.1016/j.jpeds.2016.11.008

Table 3; online.

Effect of prophylactic indomethacin on vasopressor dependent hypotension among infants born at ≤256/7 weeks gestation or ≥26 weeks gestation

Incidence of vasopressor use for at least 24 hours during days 4–7
≤256/7 weeks gestation (n=130) ≥26 weeks gestation (n=183)
Vasopressor Conservative
epoch
(n=41)
Prophylactic
epoch
(n=89)
p-value Conservative
epoch
(n=57)
Prophylactic
epoch
epoch
p-value
% % % %
Dopamine -any 37 22 0.09 21 15 0.32
Dopamine ≥6 µg/kg/min 32 13 0.01 14 9 0.28
Dopamine ≥10 µg/kg/min 22 9 0.04 14 4 0.01
Hydrocortisone * 5 2 0.65 7 1 0.03
*

Incidence of hydrocortisone use when dopamine infusion rate ≥16 µg/kg/min