Table 1.
Summary of demographic characteristics of included subjects in the compartment-based analysis.
| Baseline Characteristics | Included in compartment-level analysis (N=359 knees) | ||
|---|---|---|---|
| TOTAL | Cartilage grade 2.0 (N=265) | Cartilage grade 2.5 (N=94) | |
| Age [Mean (SD)] | 61.3 (7.6) | 61.3 (7.7) | 61.3 (7.2) |
| Gender: Female [%] | 197 (55%) | 138 (52%) | 59 (63%) |
| Gender: Male [%] | 162 (45%) | 127 (48%) | 35 (37%) |
| Race [%White] | 318 (89%) | 239 (90%) | 79 (84%) |
| Clinic site: UAB [%] | 176 (49%) | 128 (48%) | 48 (51%) |
| Clinic site: Iowa [%] | 183 (51%) | 137 (52%) | 46 (49%) |
| BMI [Mean (SD)] | 29.8 (4.6) | 29.6 (4.5) | 30.4 (4.8) |
| KL grade | |||
| 0 | 162 (45%) | 122 (46%) | 40 (43%) |
| 1 | 57 (16%) | 44 (17%) | 13 (14%) |
| 2 | 83 (23%) | 56 (21%) | 27 (29%) |
| 3 | 39 (11%) | 27 (10%) | 12 (13%) |
| 4 | 18 (5%) | 16 (6%) | 2 (2%) |
| Any Effusion-synovitis (grade ≥1) | 231 (60%) | 175 (66%) | 56 (60%) |
| Any Hoffa-synovitis (grade ≥1) | 201 (56%) | 149 (56%) | 52 (55%) |
| Any meniscal damage and/or extrusion (grade ≥1) | 179 (50%) | 134 (51%) | 45 (48%) |
| Any bone marrow lesion (grade ≥1) | 294 (82%) | 214 (80.8%) | 80 (85%) |
| Malalignment | |||
| Varus (<179°) | 212 (59%) | 160 (60%) | 52 (55%) |
| Neutral (179-181°) | 43 (12%) | 27 (10%) | 16 (17%) |
| Valgus (>181°) | 104 (29%) | 78 (30%) | 26 (28%) |