Table 1.

Quality assessment of the studies included

References	Random sequence generation	Allocation concealment*	Blinding Patient	Blinding Outcome evaluators*	Incomplete outcome data	Selective outcome reporting	Other bias
Sortino et al. [29]	Unclear	Unclear	Unclear	Unclear	Low	Low	Unclear
Barone et al. [15]	Low	Unclear	Unclear	Unclear	Low	Low	Low
Sivolella et al. [25]	Low	Unclear	Unclear	Low	Low	Low	Low
Goyal et al. [23]	Unclear	Unclear	Unclear	Low	Low	Low	Low
Itro et al. [30]	High	High	Unclear	Unclear	Unclear	High	High
Bartuli et al. [26]	Unclear	Unclear	Unclear	Unclear	Low	High	High
Rullo et al. [24]	Low	Low	Unclear	Unclear	Unclear	Low	Low
Chang et al. [27]	Low	Unclear	Unclear	Unclear	Unclear	Low	Unclear
Mantovani et al. [14]	Low	Unclear	Unclear	Unclear	Low	Low	Low
Piersanti et al. [28]	Unclear	Unclear	Unclear	Unclear	Low	Low	Low