Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Malignant mammary epithelial cells cultured in reconstituted basement membrane as spherical multicellular organoids and then embedded in collagen hydrogels placed under either 0 (unstretched - soft) or 10% strain (stretched - stiff) in a tension bioreactor. After three days, cultures were fixed and stained for actin cytoskeleton (phalloidin) and nuclei (DAPI) to assess the extent of tumor cell invasion and migration (scale bar = 20 μm).
