Table 4.
Summary of correlations among 135 analytes measured in urine and blood among Snart Foraeldre/Milieu women (n=56). Includes only biomarkers detected in greater than 75% of the study population.a
| Component 1 | Component 2 | Component 3 | |
|---|---|---|---|
| Model 1: Blood and Urine | Blood Metals: manganese, Total Hg | Blood Metals: cadmium, lead |
PFAS: PFDeA, PFNA, PFOA |
|
Urinary Metals: cobalt, lead |
PCB28 | ||
| PFAS: PFHxS, PFOS | PBDE153 | ||
| Cotinine | PAHs: 1-hydroxyphenanthrene | ||
| Persistent Pesticides: hexachlorobenzene, pp′-DDE | PAHs | Urinary Metals: total arsenic, arsenobetaine | |
| PCBs | Perchlorate | Phthalates | |
|
Phthalate: Monoethyl phthalate Parabens: methyl-paraben, propyl-paraben |
Pesticides: para-Nitrophenol, 3,5,6-Trichloro-2-pyridinol, diethylphosphate | ||
| Proportion Variance Explained | 23% | 16% | 8.1% |
| Model 2: Urine Only | PAHs | Arsenic and Arsenic Metabolites | N/A |
| Phthalate: Monoethyl phthalate | Phthalates | ||
| Parabens: methyl-paraben, propyl-paraben | Pesticides: para-Nitrophenol, 3,5,6-Trichloro-2-pyridinol, diethylphosphate | ||
| Phytoestrogen: Equol | |||
| Urinary Metals: lead | Urinary Metals: strontium | ||
| Proportion Variance Explained | 24% | 14.9% | |
| Model 3: Serum and Whole Blood Only | Blood Metals: manganese, Total Hg | All PFAS biomarkers | N/A |
| Persistent Pesticides: hexachlorobenzene, pp′-DDE | Blood Metals: cadmium, lead | ||
| PCBs | Cotinine | ||
| PBDE153 | PCB28 | ||
| Proportion Variance Explained | 24% | 15.3% |
a
Biomarkers with loadings < 0.25 are not listed.