Table 2.
Parameters | Serotonin |
PYY |
Ghrelin |
|||
---|---|---|---|---|---|---|
r | P | r | P | r | P | |
Anthropometric parameters | ||||||
Waist circumference | -0.331 | 0.025 | -0.507 | 0.000 | -0.297 | 0.045 |
WHR | -0.279 | 0.061 | -0.379 | 0.010 | -0.336 | 0.023 |
Hirsutism score | -0.340 | 0.026 | -0.421 | 0.005 | -0.381 | 0.012 |
Blood RT | ||||||
Leukocyte count | 0.265 | 0.082 | 0.164 | 0.287 | -0.008 | 0.959 |
Neutrocyte count | 0.322 | 0.033 | 0.350 | 0.020 | -0.062 | 0.689 |
Lymphocyte count | 0.205 | 0.181 | 0.028 | 0.856 | 0.059 | 0.706 |
Sex hormones | ||||||
FSH | 0.053 | 0.726 | 0.237 | 0.113 | -0.072 | 0.636 |
LH | -0.127 | 0.399 | -0.136 | 0.369 | -0.222 | 0.139 |
Testosterone | -0.312 | 0.035 | -0.371 | 0.011 | -0.627 | <0.0001 |
LH/FSH | -0.221 | 0.140 | -0.255 | 0.087 | -0.187 | 0.213 |
Metabolic parameters | ||||||
FPG | -0.157 | 0.298 | -0.065 | 0.669 | -0.012 | 0.939 |
PPG | -0.047 | 0.757 | -0.396 | 0.007 | -0.418 | 0.004 |
FINS | 0.173 | 0.251 | 0.083 | 0.583 | 0.086 | 0.568 |
P2hINS | 0.062 | 0.682 | -0.024 | 0.874 | -0.338 | 0.022 |
HOMA-beta | 0.351 | 0.017 | 0.317 | 0.032 | 0.157 | 0.298 |
HbA1c | 0.024 | 0.874 | -0.164 | 0.276 | -0.111 | 0.462 |
ALT | 0.014 | 0.926 | -0.291 | 0.050 | -0.418 | 0.004 |
AST | 0.042 | 0.784 | -0.303 | 0.041 | -0.301 | 0.042 |
TCH | 0.312 | 0.035 | -0.156 | 0.299 | -0.061 | 0.688 |
TG | 0.115 | 0.447 | -0.253 | 0.090 | -0.186 | 0.215 |
Mediators of the brain–gut axis | ||||||
Serotonin | 1.000 | / | 0.282 | 0.058 | 0.215 | 0.151 |
Ghrelin | 0.215 | 0.151 | 0.238 | 0.112 | 1.000 | / |
PYY | 0.282 | 0.058 | 1.000 | / | 0.238 | 0.112 |
Psychological scales | ||||||
SDS value | -0.185 | 0.219 | -0.135 | 0.370 | -0.034 | 0.825 |
SAS value | -0.355 | 0.016 | -0.231 | 0.122 | -0.064 | 0.671 |
After taking account of age and BMI, bold values indicate statistical significance determined by Spearman partial correlation analysis. BMI, body mass index; WHR, Waist hip ratio; Blood RT, blood routine test; FSH, follicular stimulating hormone; LH, luteinizing hormone; FPG, fasting plasma glucose; PPG, 2h postprandial plasma glucose; FINS, fasting plasma insulin; P2hINS, 2h postprandial plasma insulin; HOMA-beta, homeostasis model assessment for beta cell function; HbA1c, hemoglobin A1c; ALT, alanine aminotransferase; AST, aspartate transaminase; TCH, total cholesterol; TG, triglyceride; PYY, peptide YY; SDS, self-rating depression scale; SAS, self-rating anxiety scale; CN, control with non-obesity; CO, control with obesity; PN, PCOS with non-obesity; PO, PCOS with obesity.