Table 2.

Pathway bias analysis for [Pyr¹]apelin-13_(1–12) and apelin-17 compared to [Pyr¹]apelin-13.

Pathway		[Pyr1]apelin-13	[Pyr1]apelin-13(1–12)	Apelin-17
cAMP	LogR	9.70 ± 0.05	9.43 ± 0.10	10.28 ± 0.23
	ΔLogR	0.00 ± 0.08	−0.20 ± 0.11	0.48 ± 0.24
	RE	1	0.63	3
β-Arrestin	LogR	8.02 ± 0.13	7.89 ± 0.17	10.34 ± 0.19
	ΔLogR	0.00 ± 0.06	−0.82 ± 0.10	2.32 ± 0.07
	RE	1	0.15	208
cAMP vs. β-Arrestin	ΔΔLogR	0.00 ± 0.10	−0.62 ± 0.15	1.83 ± 0.25
	Bias Factor	1	0.24	68