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Vacuolar pH (A) and area (B) from two patients with cystic fibrosis (CF) with and without 300 μM zinc. Both patients were tested only once. Acidic vacuoles with a SFR value less than 1.2 were excluded. Between 120 and 440 vacuoles were counted for vacuolar pH, between 238 and 304 for the vacuolar area. No differences were observed between the healthy controls and the patients’ vacuolar parameters.
