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. 2017 Feb 28;8:94. doi: 10.3389/fphar.2017.00094

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Copyright © 2017 Foote, Behe, Frampton, Levine and Segal.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Measuring oxygen consumption in ClC3, KCC3, CLIC1, TRPM2, and HVCN1 deficient mouse peritoneal neutrophils induced by PMA (blue) and opsonized Candida (red). Oxygen consumption (OC) is presented as a relative percentage of the wild-type control (mean ± SEM). The numbers below indicate the number of separate experiments in brackets and number of wells recorded. Differences from WT neutrophils within each experiment: ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001. The statistics for HVCN1^-/-/CLIC1^-/- neutrophils are compared to HVCN1^-/- controls where ††p < 0.01.