Figure 2.

Indirect immunofluorescence mosaic for autoimmune blistering dermatoses in a 71-year-old woman with mucocutaneous pemphigus vulgaris (DIF of perilesional skin revealed pemphigus-type IgG1, IgG4, C3 deposits in the epidermis; ELISA serum anti-DSG1 IgG 91. 593 RU/ml, anti-DSG3 IgG above 200 RU/ml, cut-off 20 RU/ml): positive reaction with IgG (A), IgG4 (B) autoantibodies against extracellular and transmembrane domains of DSG1 expressed in transfected HEK293 cells and positive reaction with IgG (C), IgG4 (D) autoantibodies to extracellular and transmembrane domains of DSG3 expressed in transfected HEK293