Table 2.
Calculation of the diagnostic sensitivity, specificity and predictive values of original multiparametric IIF in relation to ELISA
| Diagnostic accuracy of original mosaic IIF in relation to ELISA | |||||||
|---|---|---|---|---|---|---|---|
| Original mosaic IIF (IgG) versus ELISA (IgG) | Subjects (n) | Results of ELISA | Sensitivity (%) | Specificity (%) | Positive predictive value (PPV) (%) | Negative predictive value (NPV) (%) | |
| Number of positive results | Number of negative results | ||||||
| DSG1 | 19 | 12 | 7 | 100 | 85 | 92 | 100 |
| DSG3 | 19 | 13 | 6 | 100 | 85 | 92 | 100 |
| BP180 | 37 | 36 | 1 | 91 | 100 | 100 | 25 |
| BP230 | 33 | 9 | 24 | 55 | 87 | 62 | 84 |
IIF – indirect immunofluorescence, DSG1 – desmoglein 1, DSG3 – desmoglein 3, BP180 – bullous pemphigoid antigen 180, BP230 – bullous pemphigoid antigen 230, n – number of patients.