Table 2.
Analysis of risk factors for 5‐year survival rate in 110 gastric cancer patients
| Risk factors | No. | 5‐yr S.R.† | Univariate analysis‡ P | Multivariate analysis§ | ||
|---|---|---|---|---|---|---|
| HR¶ | 95% CI | P | ||||
| ARF1 (IHC ≥ 90 score) | ||||||
| Low expression | 50 | 62.9 | 0.0288 | 1.987 | 1.045–3.776 | 0.036 |
| High expression | 60 | 40.9 | ||||
| Gross type | ||||||
| Localized | 43 | 78.8 | <0.0001 | 0.556 | 0.214–1.441 | NS |
| Infiltrative | 67 | 31.0 | ||||
| Size (cm) | ||||||
| <5 | 60 | 69.3 | <0.0001 | 1.986 | 0.929–4.247 | NS |
| ≥5 | 50 | 25.3 | ||||
| Histological type | ||||||
| Intestinal | 41 | 72.2 | 0.0001 | 2.063 | 0.924–4.607 | NS |
| Diffuse | 69 | 36.7 | ||||
| Serosal invasion | ||||||
| No (T1, T2) | 43 | 82.3 | <0.0001 | 1.584 | 0.578–4.340 | NS |
| Yes (T3, T4) | 72 | 30.3 | ||||
| Lymph node metastasis | ||||||
| No (N0) | 32 | 93.7 | <0.0001 | 9.985 | 1.913–52.125 | 0.006 |
| Yes (N1, N2, N3) | 78 | 32.4 | ||||
| Distant metastasis (pM) | ||||||
| No | 85 | 64.0 | <0.0001 | 2.502 | 1.071–5.848 | 0.034 |
| Yes | 25 | 4.2 | ||||
| Peritoneal seeding | ||||||
| No | 91 | 59.6 | <0.0001 | 1.070 | 0.441–2.597 | NS |
| Yes | 19 | 5.6 | ||||
| Vascular invasion | ||||||
| No | 91 | 57.7 | <0.0001 | 1.435 | 0.726–2.836 | NS |
| Yes | 19 | 12.1 | ||||
| Lymphatic invasion | ||||||
| No | 45 | 79.2 | <0.0001 | 0.769 | 0.295–2.004 | NS |
| Yes | 65 | 29.5 | ||||
| Perineural invasion | ||||||
| No | 71 | 64.9 | <0.0001 | 1.138 | 0.589–2.197 | NS |
| Yes | 39 | 22.7 | ||||
†Five‐year survival rate; ‡Log rank test, P value < 0.05; §Cox regression method, P value < 0.05; ¶Multivariate‐adjusted hazard ratio (HR). CI, Confidence interval; NS, not significant.