Table 4.
Mixed Effects Models for Repeated Measures
| Fixed Effects | MIDI | Satisfaction with Acute Medication |
|||||
|---|---|---|---|---|---|---|---|
| Estimate | SE | 95% CI* | Estimate | SE | 95% CI* | ||
| Intercept | 7.21 | −.11 | 7.00, 7.41 | 3.77 | 0.20 | 3.38, 4.17 | |
| Diary Day | −0.001 | 0.001 | −0.002, 0.001 | 0.003 | 0.001 | −0.0001, 0.006 | |
| Pain at Dosing | |||||||
| Mild vs. Severe | −3.42 | 0.07 | −3.60, −3.25 | 2.07 | 0.15 | 1.72, 2.42 | |
| Moderate vs. Severe | −1.84 | 0.07 | −2.01, −1.67 | 1.33 | 0.14 | 1.00, 1.66 | |
| Mild vs. Moderate | −1.59 | 0.06 | −1.72, −1.45 | 0.74 | 0.12 | 0.46, 1.02 | |
| Medication Type | |||||||
| OTC vs. MSM | 0.73 | 0.08 | 0.54, 0.93 | −1.59 | 0.19 | −2.05, −1.14 | |
| Opiate/Barbiturate vs. MSM | 1.24 | 0.10 | 1.01, 1.48 | −1.60 | 0.24 | −2.18, −1.02 | |
| OTC vs. Opiate/Barbiturate | −0.51 | 0.10 | −0.76, −0.26 | 0.01 | 0.26 | −0.61, 0.63 | |
| Pain at Dosing X Medication† | |||||||
| Mild Pain at Dosing | OTC vs. MSM | 1.57 | 0.09 | 1.40, 1.75 | −2.61 | 0.20 | −3.10, −2.12 |
| Opiate/Barbiturate vs. MSM | 2.20 | 0.13 | 1.89, 2.52 | −3.03 | 0.31 | −3.77, −2.29 | |
| OTC vs. Opiate/Barbiturate | −0.63 | 0.14 | −0.96, −0.30 | 0.42 | 0.32 | −0.36, 1.20 | |
| Moderate Pain at Dosing | OTC vs. MSM | 0.52 | 0.09 | 0.30, 0.74 | −1.40 | 0.21 | −1.91, −0.90 |
| Opiate/Barbiturate vs. MSM | 1.43 | 0.13 | 1.13, 1.73 | −1.42 | 0.29 | −2.12, −0.73 | |
| OTC vs. Opiate/Barbiturate | −0.91 | 0.13 | −1.23, −0.60 | 0.02 | 0.31 | −0.72, 0.75 | |
| Severe Pain at Dosing | OTC vs. MSM | 0.11 | 0.15 | −0.45, 0.47 | −0.77 | 0.32 | −1.53, −0.01 |
| Opiate/Barbiturate vs. MSM | 0.10 | 0.16 | −0.28, 0.48 | −0.36 | 0.32 | −1.13, 0.41 | |
| OTC vs. Opiate/Barbiturate | 0.01 | 0.17 | −0.40, 0.42 | −0.41 | 0.37 | −1.30, 0.48 | |
| OTC | Mild vs. Severe | −3.15 | 0.12 | −3.44, −2.86 | 1.73 | 0.26 | 1.11, 2.35 |
| Moderate vs. Severe | −2.01 | 0.12 | −2.30, −1.72 | 1.26 | 0.26 | 0.64, 1.88 | |
| Mild vs. Moderate | −1.14 | 0.08 | −1.33, −0.95 | 0.47 | 0.16 | 0.09, 0.85 | |
| Opiate/Barbiturate | Mild vs. Severe | −2.51 | 0.15 | −2.87, −2.14 | 0.90 | 0.31 | 0.17, 1.64 |
| Moderate vs. Severe | −1.09 | 0.14 | −1.43, −0.74 | 0.83 | 0.28 | 0.18, 1.49 | |
| Mild vs. Moderate | −1.42 | 0.14 | −1.75, −1.09 | 0.07 | 0.30 | −0.62, 0.76 | |
| MSM | Mild vs. Severe | −4.61 | 0.10 | −4.85, −4.37 | 3.57 | 0.17 | 3.15, 4.00 |
| Moderate vs. Severe | −2.42 | 0.10 | −2.66, −2.18 | 1.90 | 0.17 | 1.48, 2.31 | |
| Mild vs. Moderagte | −2.20 | 0.06 | −2.34, −2.05 | 1.68 | 0.11 | 1.42, 1.94 | |
†
Pair-wise comparisons displayed by levels of Pain at Dosing and Medication Use. Comparisons across levels of Pain at Dosing and Medication Use are not displayed.
*
For pairwise comparisons, 95% Confidence Intervals adjusted using Bonferroni correction