Table 2.

Effect of EOVA on hot-plate test

Groups	Dose (mg/kg)	Reaction time (sec)
		0hr	0.5hr	1hr	1.5hr	24hr	48hr
Control	-	14.96±1.21	13.14±1.25	13.53±1.67	14.46±0.72	13.15±0.63	15.03±1.11
EOVA	25	10.68±0.45	17.75±1.17	13.21±0.89	14.46±1.05	10.15±0.51	10.65±0.95
	50	16.90±2.38	19.56±1.94**	14.31±0.69	13.53±0.86	14.46±1.30	11.31±0.58
	100	14.62±1.63	15.62±1.42	14.96±0.86	17.93±1.52	12.84±0.73	11.25±0.75
	200	9.65±0.73	14.87±1.52	20.50±1.31**	14.84±1.12	18.73±1.39*	11.50±0.55
Morphine	7.5	12.62±1.72***	24.50±1.50***	27.62±1.45**	24.62±1.34**	25.50±1.99	22.62±1.46*

Values represent mean ± SEM. p < 0.05;

^** p < 0.01; and

^*** p<0.001 as compared to the control group (ANOVA, Student-Newman Keuls).