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Dexmedetomidine significantly inhibited the release of MCP-1 in activated astrocytes. RT-PCR shows that dexmedetomidine significantly inhibited the release of MCP-1 in activated astrocytes. Data represent mean ± standard error of the mean of four independent experiments. ###P < 0.001 versus control group; ∗∗∗P < 0.001 versus LPS 100 ng/ml group.
