Table 3.
Pregnancy outcome with any raised antibody and with TSH < 2.5 mIU/L.
| Variable | No positive antibody | ≥1 positive antibody | p value | Odds ratio | LC | UC | ||
|---|---|---|---|---|---|---|---|---|
| (N = 742) | (N = 191) | |||||||
| n | % | n | % | |||||
| TGAb > 60 IU/mL | 0 | 0.0% | 111 | 58.1 | NA | |||
| TPOAb > 60 IU/mL | 0 | 0.0% | 141 | 73.8 | NA | |||
| GTT positive (GD) | 28 | 3.8% | 7 | 3.7 | 0.956 | 1.0 | 0.4 | 2.3 |
| Nulliparous | 281 | 38.2% | 62 | 33.5 | 0.236 | 0.8 | 0.6 | 1.1 |
| APGAR 1 minute < 7 | 24 | 3.3% | 8 | 4.3 | 0.495 | 1.3 | 0.6 | 3.0 |
| APGAR 5 minutes < 7 | 5 | 0.7% | 2 | 1.1 | 0.582 | 1.6 | 0.3 | 8.2 |
| Fetal death in utero (FDIU) | 3 | 0.4% | 2 | 1.1 | 0.274 | 2.6 | 0.4 | 15.8 |
| Stillbirth or FDIU | 10 | 1.4% | 3 | 1.6 | 0.807 | 1.2 | 0.3 | 4.3 |
| Pregnancy induced hypertension | 15 | 2.0% | 3 | 1.6 | 0.694 | 0.8 | 0.2 | 2.7 |
| Premature labour | 13 | 1.8% | 3 | 1.6 | 0.817 | 0.9 | 0.3 | 3.2 |
| Antepartum haemorrhage | 3 | 0.4% | 2 | 1.1 | 0.274 | 2.6 | 0.4 | 15.8 |
| Abruption | 1 | 0.1% | 0 | 0.0 | NA | |||
| SROM | 18 | 2.4% | 1 | 0.5 | 0.990 | 0.2 | 0.0 | 1.6 |
| SGA | 10 | 1.4% | 4 | 2.1 | 0.443 | 1.6 | 0.5 | 5.1 |
TSH, thyroid stimulating hormone; TGAb, anti-thyroglobulin antibodies; TPOAb, thyroperoxidase antibodies; SROM, spontaneous rupture of membranes; SGA, small for gestational age; FDIU, fetal death in utero.