Table 1.
Summary of MαF-Ig mAb.
| mAb | Ig subclass | VHa | VLa | Specificity |
|---|---|---|---|---|
| 4-B10 | IgG1 | IGHV4-1 | IGKV6-13 | Light chain (Igκ)c,d |
| 4-D11 | IgG1 | IGHV2-3 | IGKV16-104 | Light chain (Igλ)d |
| 4-E3b | IgG1 | IGHV1-20 or IGHV1-37 | IGKV3-12 | Light chain (Igκ)d |
| 6-B5 | IgG1 | IGHV5-6 | IGKV19-93 | Ferret Ig |
| 6-B7 | IgG1 | IGHV5-6 | NDe,f | Heavy chain (IgH)g |
| 6-H5 | IgG1 | IGHV5-17 | IGKV5-48 | Light chain (Igλ)d |
| 8-H9 | IgG1 | IGHV14-3 | IGKV6-32 | Light chain (Igλ)c,d |
| 11-E3 | IgG1 | IGHV1S81 | IGKV6-17 | Heavy chain (Igγ)c |
a: identified using IMGT V-Quest (see [21]). b: unable to unambiguously assign IGHV. c: determined by western blot. d: determined by flow cytometry. e: not determined. f: negative for intracellular Igκ by flow cytometry. g: determined by competitive ELISA.