Table 1.
List of selected tumor suppressor microRNAs and oncomiRs in cancer
Cancer type | |
OncomiRs | |
miR17-92[108] | B-cell lymphoma, small cell lung cancer, colon cancer, gastric cancer |
miR-21[107] | Breast, colon and lung cancer, glioblastoma |
miR-106[133] | Gastric cancer, colorectal cancer |
miR-10b[113] | Breast cancer |
miR-191[134,135] | Human colorectal and breast cancer |
Tumor suppressor miRNAs | |
let-7[105,106] | Lung cancer, Burkitt lymphoma |
miR-15a, miR16-1[103,104] | CLL, prostate cancer, mesothelioma |
miR-29[136] | Lung cancer, breast cancer |
miR-34a[116] | Prostate cancer, mesothelioma, HCC |
miR-126[114] | Lung and breast cancer |
Both O and TS | |
miR-24[137,138] | Breast cancer, glioma (O) |
Laryngeal carcinoma (TS) | |
miR-125[122,123] | Pancreatic and prostate cancer (O) |
Melanoma, osteosarcoma, ovarian cancer (TS) | |
miR-155[120,121] | Lymphoma, breast cancer (O) |
Melanoma, ovarian and gastric cancer (TS) | |
miR-221/222[139] | Glioblastoma, HCC, breast cancer (O) |
Tongue squamous cell carcinoma (TS) |
CLL: Chronic lymphocytic leukemia; HCC: Hepatocellular carcinoma; O: OncomiR; TS: Tumor suppressor miRNA.