Table 2. Pre and Post Ablation Methacoline.

The positive control demonstrates the efficacy of methacholine to induce bronchial constriction, in normal (pre-ablation) airways. The experimental demonstrates the effect of ablation to acutely impair the bronchoconstrictive response of MCH, measured before and after ablation. Airway measurements made at 15 cm of PEEP during a breath hold at under I.V. anesthesia with neuromuscular blockade.

Positive Control: Pre-ablation control vs Pre-ablation MCH Constricts Airways (diameter cm)
Location 1	0.84 control to 0.67 post-MCH (−23%)
Location 2	0.76 control to 0.48 post MCH (−37%)
Experimental: Pre-ablation MCH vs Post-ablation MCHMCH(diameter cm)
Location 1	0.76 to 1.14 (+50%)
Location 2	0.76 to 1.19 (+57%)