Table 1.

Platelet a-granule content

Type	Examples
Adhesive proteins	Von Willebrand factor, fibrinogen, trombospondi-1, trombospondin-2, laminin-8
Growth factors	Epidermal growth factor (EGF), insulin-like growth factor 1 (IGF-1), hepatocyte growth factor (HGF), transforming growth factor ß (TGF-ß)
Angiogenic factors	Vascular endothelium growth factor (VEGF), platelet-derived growth factor (PDGF), fibroblast growth factor (FGF)
Chemokines	CCL5 (RANTES), CCL-3 (MIP-1a), CCL-2 (MCP-1), CCL-7 (MCP-3), CXCL8 (IL-8), CXCL2 (MIP-2), CXCL6 (LIX), CXCL-1 (GRO-a), CXCL5 (ENA-78), CXCL-12 (SDF-1a), CXCL4 (PF4)
Clotting factors and their inhibitors	Factor V, factor IX, antithrombin, factor S, protease nexin-1, protease nexin-2, tissue factor pathway inhibitor,
Integral membrane proteins	aIIb3, GPIba-IX-V, GPVI, TLT-1, p-selectin
Immune mediators	Complement C3 precursor, complement C4 precursor, factor D, factor H, C1 inhibitor, IgG