Table 5.
Negative impact of NVP on daily life functioning and willingness to get pregnant again
| PUQE | |||||
|---|---|---|---|---|---|
| Totalb | Mild | Moderate | Severe | p-valuea | |
| N = 712 n (%) | N = 62 n (%) | N = 439 n (%) | N = 210 n (%) | ||
| 1. Taking care of household chores | |||||
| No impact | 29 (4.1) | 14 (22.6) | 14 (3.2) | 1 (0.5) | <0.001 |
| Minor impact | 150 (21.1) | 37 (59.7) | 103 (23.5) | 10 (4.8) | |
| Major impact | 533 (74.9) | 11 (17.7) | 322 (73.3) | 199 (94.8) | |
| 2. Social life | |||||
| No impact | 44 (6.2) | 18 (29.0) | 23 (5.2) | 3 (1.4) | <0.001 |
| Minor impact | 155 (21.8) | 34 (54.8) | 103 (23.5) | 17 (8.1) | |
| Major impact | 513 (72.1) | 10 (16.1) | 313 (71.3) | 190 (90.5) | |
| 3. Relationship with partner c, n=682 | |||||
| No impact | 134 (19.6) | 23 (38.3) | 77 (18.2) | 34 (17.1) | <0.001 |
| Minor impact | 306 (44.9) | 32 (53.3) | 193 (45.7) | 80 (40.2) | |
| Major impact | 242 (35.5) | 5 (8.3) | 152 (36.0) | 85 (42.7) | |
| 4. Ability to care for children d, n=351 | |||||
| No impact | 31 (8.8) | 10 (32.3) | 16 (7.7) | 5 (4.5) | <0.001 |
| Minor impact | 97 (27.6) | 17 (54.8) | 67 (32.2) | 13 (11.6) | |
| Major impact | 223 (63.5) | 4 (12.9) | 125 (60.1) | 94 (83.9) | |
| 5. Work capacity e, n=671 | |||||
| No impact | 28 (4.2) | 8 (13.8) | 20 (4.9) | 0 (0.0) | <0.001 |
| Minor impact | 147 (21.9) | 40 (69.0) | 95 (23.2) | 12 (5.9) | |
| Major impact | 496 (73.9) | 10 (17.2) | 294 (71.9) | 191 (94.1) | |
| 6. Sick leave due to NVP f, n=649 | |||||
| No | 221 (34.1) | 50 (84.7) | 153 (38.8) | 18 (9.2) | <0.001 |
| Yes | 428 (65.9) | 9 (15.3) | 241 (61.2) | 178 (90.8) | |
| 7. Considered to terminate the pregnancy due to NVP | |||||
| No | 608 (85.5) | 62 (100.0) | 393 (89.5) | 153 (72.9) | <0.001 |
| Yes | 100 (14.1) | 0 (0.0) | 44 (10.0) | 56 (26.7) | |
| Unsure | 3 (0.4) | 0 (0.0) | 2 (0.5) | 1 (0.5) | |
| 8. Consider not to get pregnant again | |||||
| No | 333 (46.8) | 54 (87.1) | 233 (53.1) | 46 (21.9) | <0.001 |
| Yes | 353 (49.6) | 6 (9.7) | 188 (42.8) | 159 (75.7) | |
| Unsure | 25 (3.5) | 2 (3.2) | 18 (4.1) | 5 (2.4) | |
Abbreviations: CI, confidence interval; PUQE, 24 h Pregnancy-Unique Quantification of Emesis; NVP, nausea and vomiting of pregnancy
aChi-square test or Fisher’s exact test when expected count were less than 5. Bold p-values indicate statistically significant differences between the groups
bThe sums do not always add up to total due to missing (“not relevant”)
c3.8% responded “not relevant”
d52.3% did not have any children
e6.8% responded “not relevant”
f8.8% responded “not relevant”