Figure 2.

Inhibition of CRC colony formation by CUDC-907 when combined with 5-FU. (a) Relative cell survival as determined by colony forming assay at different cell counts of HCT116 (15, 30, 60, 120, 240, and 500) cells/well treated with 10 nM CUDC-907 alone, 1.5 μM 5-FU alone, or with combination of CUDC-907 and 5-FU. (b) Image representing colony formation of HCT116 cells treated with 10 nM CUDC-907 alone, 1.5 μM 5-FU alone, or with combination of CUDC-907 and 5-FU