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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Prev Vet Med. 2017 Jan 10;138:17–27. doi: 10.1016/j.prevetmed.2017.01.007

Table 3.

Dominance rankings of the top 10 control programs for Mycobacterium avium subsp. paratuberculosis based on maximizing Net Present Value of dairy herds over 5 years, by herd size and initial prevalence. Score refers to the number of potential control programs (out of 122) for which a control program is either first or second order dominant. Unless otherwise stated, standard hygiene was used (as opposed to moderate or improved), animals were tested annually (as opposed to biannually), and testing was discontinued after 5 negative whole-herd tests (as opposed to continuous testing). Testing options are ELISA, PCR, or fecal culture (FC). Culling options are to cull all positive animals (cull all), cull only high-positive animals (cull high), or cull animals after their second positive test (cull repeat).

100 Head 1000 Head
10% Prevalence 20% Prevalence 10% Prevalence 20% Prevalence
Control Score Control Score Control Score Control Score
ELISA, cull high 110 Continuous ELISA, cull all 116 Continuous ELISA, cull repeat 120 Continuous ELISA, cull all 115
ELISA, cull repeat 107 Continuous biannual ELISA, cull repeat 114 Continuous ELISA, cull all 117 Continuous ELISA, cull repeat 115
PCR, cull repeat 103 Biannual ELISA, cull all 113 Continuous biannual ELISA, cull all 114 Continuous ELISA, cull high 114
ELISA, cull all 97 Biannual ELISA, cull high 113 Nothing 113 Biannual ELISA, cull repeat 113
Nothing 82 Continuous ELISA, cull high 113 Continuous biannual ELISA, cull repeat 112 Biannual ELISA, cull high 112
Biannual ELISA, cull all 80 Continuous biannual ELISA, cull high 113 Biannual ELISA, cull repeat 109 Continuous biannual ELISA, cull repeat 112
FC, cull repeat 79 Continuous biannual ELISA, cull all 112 Continuous PCR, cull high 106 Continuous biannual ELISA, cull all 109
Biannual ELISA, cull repeat 78 Continuous ELISA, cull repeat 109 Continuous ELISA, cull high 105 Continuous FC, cull high 107
ELISA, cull all, moderate hygiene 75 Biannual ELISA, cull repeat 108 ELISA, cull high 104 Continuous PCR, cull high 106
ELISA, cull high, moderate hygiene 75 Continuous PCR, cull high 106 Moderate hygiene 104 Continuous PCR, cull repeat 106