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. Author manuscript; available in PMC: 2017 May 26.
Published in final edited form as: J Med Chem. 2016 Apr 22;59(10):5102–5108. doi: 10.1021/acs.jmedchem.6b00182

Scheme 2. Synthesis of Mosher Esters 19a and 19ba.

Scheme 2

aReagents and conditions: (a) (R)-Mosher acid chloride, Et3N, DMAP, DCM, rt, overnight, 80%. (b) (S)-Mosher acid chloride, Et3N, DMAP, DCM, rt, overnight, 88%.