Table I.
Up‐regulated genes induced in SHP‐2IEC‐KO colons (n = 3 mice per group)
| Gene | Identification | Relative expression | P |
|---|---|---|---|
| Defensin. alpha. 24 (Defa24) | 1450631_x_at | 4.15 | 2.80−6 |
| Indoleamine 2.3‐dioxygenase 1 (Ido1) | 1420437_at | 2.80 | 0.014 |
| Interleukin 1 receptor‐like 1 (Il1rl1) | 1422317_a_at | 2.57 | 0.021 |
| Chemokine (C‐ X‐C motif) ligand 5 (Cxcl5) | 1419728_at | 2.39 | 0.047 |
| Liver‐expressed antimicrobial peptide 2 (Leap2) | 1427480_at | 2.34 | 2.75−4 |
| Regenerating islet‐derived 3 beta (Reg3β) | 1416297_s_at | 2.12 | 3.50−5 |
| Leukocyte cell‐derived chemotaxin 2 (Lect2) | 1449492_a_at | 2.04 | 9.81−5 |
| Chemokine (C‐C motif) ligand 20 (Ccl20) | 1422029_at | 1.93 | 3.53−3 |
| Complement component 2 (C2) | 1416051_at | 1.65 | 9.99−5 |
| Chemokine (C‐C motif) ligand 25 (Ccl25) | 1418777_at | 1.65 | 3.10−4 |
| Regenerating islet‐derived 3 gamma (Reg3γ) | 1448872_at | 1.63 | 0.014 |
| Alpha‐2‐HS‐ glycoprotein (Ahsg) | 1455093_a_at | 1.58 | 0.041 |
| Interleukin 18 receptor 1 (Il18r1) | 1421628_at | 1.55 | 1.77−3 |
| Radical S‐ adenosyl methionine domain containing 2 (Rsad2) | 1436058_at | 1.54 | 0.025 |
| Interferon regulatory factor 7 (Irf7) | 1417244_a_at | 1.51 | 7.75−4 |