Table II.

Microbiota composition in SHP‐2^IEC‐KO mice compared to control littermates (n ≥ 5 mice per group)

		2 weeks			4 weeks
		Mean (Ct)	Standard deviation	P‐value	Mean (Ct)	Standard deviation	P‐value
Target bacterial group
–
Total bacteria	Control	15.32	1.65	0.132	13.09	0.97	0.257
	SHP‐2IEC‐KO	16.57	1.64		15.04	2.27
Lactobacillus	Control	21.22	1.68	0.063	21.13	1.27	0.063
	SHP‐2IEC‐KO	23.70	1.80		25.82	3.11
Bacteroides fragilis	Control	20.70	3.26	0.762	18.50	2.32	0.999
	SHP‐2IEC‐KO	23.01	7.46		18.75	0.99
Clostridium leptum	Control	17.41	1.98	0.065	16.18	0.56	0.006
	SHP‐2IEC‐KO	20.73	2.82		19.72	2.83
Clostridium coccoides	Control	16.80	1.84	0.24	13.09	0.60	0.006
	SHP‐2IEC‐KO	21.57	5.54		18.67	4.00
Enterobacteriaceae	Control	22.85	3.47	0.029	29.02	2.64	0.012
	SHP‐2IEC‐KO	18.21	1.79		20.84	4.19